Professional background
Professor Ahmed Toosy studied medicine at Cambridge and St George's Medical School before undertaking specialist neurology training in London.
He is currently a clinical senior lecturer at University College London and holds honorary consultant posts at The National Hospital for Neurology and Neurosurgery and Moorfields Eye Hospital.
He has sub-specialty interests in demyelinating disorders and neuro-ophthalmology.
Specialties
Research interests
Mechanisms of disability and recovery in demyelination (multiple sclerosis) and visual disorders.
Publications
Adaptive cortical plasticity in higher visual areas after acute optic neuritis.
Toosy AT, Hickman SJ, Miszkiel KA, Jones SJ, Plant GT, Altmann DR, Barker GJ, Miller DH, Thompson AJ.
Ann Neurol. 2005 May;57(5):622-33.
Neuroplasticity predicts outcome of optic neuritis independent of tissue damage.
Jenkins TM, Toosy AT, Ciccarelli O, Miszkiel KA, Wheeler-Kingshott CA, Henderson AP, Kallis C, Mancini L, Plant GT, Miller DH, Thompson AJ.
Ann Neurol. 2010 Jan;67(1):99-113.
Assessing neuronal metabolism in vivo by modeling imaging measures.
Ciccarelli O, Toosy AT, De Stefano N, Wheeler-Kingshott CA, Miller DH, Thompson AJ.
J Neurosci. 2010 Nov 10;30(45):15030-3.
Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions.
Thompson AJ, Toosy AT, Ciccarelli O.
Lancet Neurol. 2010 Dec;9(12):1182-99.
Assessing neuronal metabolism in vivo by modeling imaging measures.
Ciccarelli O, Toosy AT, De Stefano N, Wheeler-Kingshott CA, Miller DH, Thompson AJ.
J Neurosci. 2010 Nov 10;30(45):15030-3.
A longitudinal functional MRI study of non-arteritic anterior ischaemic optic neuropathy patients.
Aguirregomozcorta M, Mancini L, Jenkins TM, Hickman SJ, Ciccarelli O, Plant GT, Thompson AJ, Toosy AT.
J Neurol Neurosurg Psychiatry. 2011 Aug;82(8):905-13.
Early pericalcarine atrophy in acute optic neuritis is associated with conversion to multiple sclerosis.
Jenkins TM, Ciccarelli O, Atzori M, Wheeler-Kingshott CA, Miller DH, Thompson AJ, Toosy AT.
J Neurol Neurosurg Psychiatry. 2011 Sep;82(9):1017-21.
Optic Neuritis
Ahmed T Toosy, Deborah F Mason and David H Miller
Lancet Neurology. 2014 Jan;13(1):83-99.
Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial.
Raftopoulos R, Hickman SJ, Toosy A, Sharrack B, Mallik S, Paling D, Altmann DR, Yiannakas MC, Malladi P, Sheridan R, Sarrigiannis PG, Hoggard N, Koltzenburg M, Gandini Wheeler-Kingshott CA, Schmierer K, Giovannoni G, Miller DH, Kapoor R
Lancet Neurol. 2016 Mar;15(3):259-69.
Longitudinal evidence of anterograde trans-synaptic degeneration after optic neuritis
C. Tur, O. Goodkin, D.R. Altmann, T.M. Jenkins, K Miszkiel, A. Mirigliani, C. Fini, C.A.M. Gandini Wheeler-Kingshott, A.J. Thompson, O. Ciccarelli, A.T. Toosy
Brain 2016 Mar;139(Pt 3):816-28 .
Structural network disruption markers explain disability in multiple sclerosis.
Charalambous T, Tur C, Prados F, Kanber B, Chard DT, Ourselin S, Clayden JD, A M Gandini Wheeler-Kingshott C, Thompson AJ, Toosy AT
J Neurol Neurosurg Psychiatr; 2019 Feb;90(2):219-226.