The department of uro-neurology uniquely bridges the disciplines of neurology, urology, uro-gynaecology, neurogastroenterology, pelvic neurology/neurophysiology, psychology and pelvic physiotherapy, and offers a holistic, multidisciplinary approach to the evaluation and treatment of bladder, bowel and sexual dysfunction in individuals with established and suspected neurological disorders.

The team consists of consultants, nurses, clinical scientists performing urodynamics and neurophysiology, junior doctors, a psychologist and pelvic floor physiotherapist.

Service management

  • David O'Keefe


Department of Uro-Neurology
The National Hospital for Neurology and Neurosurgery
Ground Floor, Queen Mary Wing  
Queen Square 
London, WC1N 3BG

Other referral information

Tertiary referrals

Referrals come from urologists, neurologists and gynaecologists across the UK.

Referral address

Department of Uro-Neurology 
The National Hospital for Neurology and Neurosurgery 
Queen Square 

The department sees individuals  across a wide range of  neurological disorders that include multiple sclerosis and related inflammatory disorders, dementias, Parkinson’s Disease and Parkinson's plus syndromes, spinal cord and brain tumours  and traumatic disorders such as cauda equina injury. Bladder problems  such as urinary incontinence and urinary retention are common in these conditions and the service offers a comprehensive urological assessment that includes urodynamics testing.

The department  offers a holistic approach to the evaluation  and treatment of urinary retention in young women, many of whom are eventually found to have a primary disorder of urethral sphincter relaxation (sometimes called Fowler’s syndrome).

A growing number of individuals with unexplained bladder, sexual, bowel and pelvic floor dysfunction  are being referred for evaluating a possible neurological cause, and the department offers a dedicated pelvic neurology service that  includes pelvic neurological examination, pelvic neurophysiology testing evaluating the afferent and efferent sacral somatic innervation and urodynamics testing, and has links with neuroradiology.

Different treatments for managing bladder problems, ranging from conservative measures including pelvic floor physiotherapy and catheterization to tibial nerve stimulation (percutaneous and transcutaneous; PTNS and TTNS), botulinum toxin (Botox) into the bladder (detrusor) and urethral sphincter and sacral neuromodulation, are offered by the service.

Bowel dysfunction is common following neurological disorders and  the department offers a dedicated neurogastroenterology service.

The department also runs a dedicated clinic for women reporting sexual difficulties following neurological disease.

Uro-neurology has close links with allied services within UCLH such as functional urology, gynaecology, andrology, gastroenterology and the GI physiology unit for testing, autonomics and pain management.

•    Neurogenic overactive bladder/detrusor overactivity 
•    Non-obstructive urinary retention 
•    Neurogenic sexual dysfunction in men and women
•    Neurogenic bowel dysfunction

The department has a strong academic component and is heavily involved in teaching and training of doctors, nurses and other health care professionals. Through its links with UCL and the UCLH/UCL NIHR Biomedical Research Centre, the department is involved in clinical trials and  original research exploring the neural control of bladder functions, urogenital dysfunction following neurological disease and non-surgical management options.

Ms Sohier Elneil Uro-neurology, urogynaecology
Professor Anton Emmanuel Neurogastroenterology
Professor Jalesh N. Panicker Uro-neurology, pelvic neurology, pelvic neurophysiology 
Mrs Mahreen Pakzad Uro-neurology, urology
Dr Sara Simeoni Uro-neurology, pelvic neurology, pelvic neurophysiology