Professional background
Mr Dimitrios Mavrelos is a consultant obstetrician and gynaecologist and accredited sub-specialist in reproductive medicine and surgery.
He studied medicine at the University of Oxford and Guy's King's St Thomas' School of Medicine. He completed his specialty and subspecialty training in London training with international experts in gynaecological ultrasound, minimal access surgery to improve fertility and in vitro fertilisation.
Alongside his clinical work, Mr Mavrelos is an honorary Senior Lecturer at University College London and has published innovative scientific articles and book chapters on the diagnosis and management of endometriosis, the diagnosis and management of early pregnancy complications and the impact of gynaecological disorders on fertility.
He lectures nationally and internationally on these subjects and continues leading an active research programme on improving outcomes of IVF cycles.
Specialties
Research interests
1: Saridogan E, Mavrelos D, Jurkovic D. To decide on the value of hysteroscopic
septum resection we need prospective data. Hum Reprod. 2020 Sep 24:deaa229. doi:
10.1093/humrep/deaa229. Epub ahead of print. PMID: 32968759.
2: Latif S, Mavrelos D. Endometriosis-associated pain in women undergoing
hysterectomy. BJOG. 2020 Sep 19. doi: 10.1111/1471-0528.16514. Epub ahead of
print. PMID: 32949081.
3: Balachandren N, Salman M, Diu NL, Schwab S, Rajah K, Mavrelos D. Ovarian
reserve as a predictor of cumulative live birth. Eur J Obstet Gynecol Reprod
Biol. 2020 Sep;252:273-277. doi: 10.1016/j.ejogrb.2020.06.063. Epub 2020 Jul 2.
PMID: 32645642.
4: Hirsch M, Wojtaszewska A, Saridogan E, Mavrelos D, Barker C, Duffy JMN.
Googling fibroids: A critical appraisal of information available on the
internet. Eur J Obstet Gynecol Reprod Biol. 2020 Jul;250:224-230. doi:
10.1016/j.ejogrb.2020.04.004. Epub 2020 Apr 18. PMID: 32473505.
5: Rajah K, Dizdar M, Balachandren N, Kriedt K, Saridogan E, Mavrelos D. Who is
at risk of endometrial cavity breach at laparoscopic myomectomy? Facts Views Vis
Obgyn. 2019 Sep;11(3):229-233. PMID: 32082529; PMCID: PMC7020946.
6: Burt E, Davies MC, Yasmin E, Cameron-Pimblett A, Mavrelos D, Talaulikar V,
Conway GS. Reduced uterine volume after induction of puberty in women with
hypogonadism. Clin Endocrinol (Oxf). 2019 Dec;91(6):798-804. doi:
10.1111/cen.14092. Epub 2019 Oct 9. PMID: 31487390.
7: Irungu S, Mavrelos D, Worthington J, Blyuss O, Saridogan E, Timms JF.
Discovery of non-invasive biomarkers for the diagnosis of endometriosis. Clin
Proteomics. 2019 Apr 6;16:14. doi: 10.1186/s12014-019-9235-3. PMID: 30992697;
PMCID: PMC6451201.
8: Knez J, Saridogan E, Van Den Bosch T, Mavrelos D, Ambler G, Jurkovic D.
ESHRE/ESGE female genital tract anomalies classification system-the potential
impact of discarding arcuate uterus on clinical practice. Hum Reprod. 2018 Apr
1;33(4):600-606. doi: 10.1093/humrep/dey043. PMID: 29514262.
9: Mavrelos D, Holland TK, O'Donovan O, Khalil M, Ploumpidis G, Jurkovic D,
Khalaf Y. The impact of adenomyosis on the outcome of IVF-embryo transfer.
Reprod Biomed Online. 2017 Nov;35(5):549-554. doi: 10.1016/j.rbmo.2017.06.026.
Epub 2017 Jul 29. PMID: 28802706.
10: Mavrelos D, Al Chami A, Talaulikar V, Burt E, Webber L, Ploubidis G, Yasmin
E. Variation in antral follicle counts at different times in the menstrual
cycle: does it matter? Reprod Biomed Online. 2016 Aug;33(2):174-9. doi:
10.1016/j.rbmo.2016.04.012. Epub 2016 May 5. PMID: 27184084.
11: Jurkovic D, Knez J, Appiah A, Farahani L, Mavrelos D, Ross JA. Surgical
treatment of Cesarean scar ectopic pregnancy: efficacy and safety of ultrasound-
guided suction curettage. Ultrasound Obstet Gynecol. 2016 Apr;47(4):511-7. doi:
10.1002/uog.15857. PMID: 26764166.
12: Naftalin J, Hoo W, Nunes N, Holland T, Mavrelos D, Jurkovic D. Association
between ultrasound features of adenomyosis and severity of menstrual pain.
Ultrasound Obstet Gynecol. 2016 Jun;47(6):779-83. doi: 10.1002/uog.15798. PMID:
26499878.
13: Helmy S, Mavrelos D, Sawyer E, Ben-Nagi J, Koch M, Day A, Jurkovic D. Serum
Human Chorionic Gonadotropin (?- hCG) Clearance Curves in Women with
Successfully Expectantly Managed Tubal Ectopic Pregnancies: A Retrospective
Cohort Study. PLoS One. 2015 Jul 2;10(7):e0130598. doi:
10.1371/journal.pone.0130598. PMID: 26135923; PMCID: PMC4489732.
14: Mavrelos D, Memtsa M, Helmy S, Derdelis G, Jauniaux E, Jurkovic D. ?-hCG
resolution times during expectant management of tubal ectopic pregnancies. BMC
Womens Health. 2015 May 21;15:43. doi: 10.1186/s12905-015-0200-7. PMID:
25994203; PMCID: PMC4443555.
15: Mavrelos D, Saridogan E. Treatment of endometriosis in women desiring
fertility. J Obstet Gynaecol India. 2015 Feb;65(1):11-6. doi:
10.1007/s13224-014-0652-y. Epub 2015 Jan 22. PMID: 25737616; PMCID: PMC4342385.
16: Pateman K, Moro F, Mavrelos D, Foo X, Hoo WL, Jurkovic D. Natural history of
ovarian endometrioma in pregnancy. BMC Womens Health. 2014 Oct 15;14:128. doi:
10.1186/1472-6874-14-128. PMID: 25315259; PMCID: PMC4287586.
17: Moro F, Mavrelos D, Pateman K, Holland T, Hoo WL, Jurkovic D. Prevalence of
pelvic adhesions on ultrasound examination in women with a history of Cesarean
section. Ultrasound Obstet Gynecol. 2015 Feb;45(2):223-8. doi:
10.1002/uog.14628. Epub 2014 Dec 26. PMID: 25042444.
18: Ludovisi M, Mavrelos D, Jurkovic D. Re: factors affecting visualization of
postmenopausal ovaries: descriptive study from the multicenter United Kingdom
Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Ultrasound Obstet
Gynecol. 2014 May;43(5):600. doi: 10.1002/uog.13321. PMID: 24789306.
19: Naftalin J, Hoo W, Pateman K, Mavrelos D, Foo X, Jurkovic D. Is adenomyosis
associated with menorrhagia? Hum Reprod. 2014 Mar;29(3):473-9. doi:
10.1093/humrep/det451. Epub 2014 Jan 8. PMID: 24408315.
20: Holland TK, Cutner A, Saridogan E, Mavrelos D, Pateman K, Jurkovic D.
Ultrasound mapping of pelvic endometriosis: does the location and number of
lesions affect the diagnostic accuracy? A multicentre diagnostic accuracy study.
BMC Womens Health. 2013 Oct 29;13:43. doi: 10.1186/1472-6874-13-43. PMID:
24165087; PMCID: PMC3815071.
21: Mavrelos D, Cohen H, Pateman K, Hoo W, Foo X, Jurkovic D. Diagnosis of
uterine vein thrombosis on transvaginal ultrasound. Ultrasound Obstet Gynecol.
2013 Oct;42(4):480-3. doi: 10.1002/uog.12520. Epub 2013 Aug 12. PMID: 23716379.
22: Pateman K, Mavrelos D, Hoo WL, Holland T, Naftalin J, Jurkovic D.
Visualization of ureters on standard gynecological transvaginal scan: a
feasibility study. Ultrasound Obstet Gynecol. 2013 Jun;41(6):696-701. doi:
10.1002/uog.12468. Epub 2013 May 7. PMID: 23554048.
23: Mavrelos D, Nicks H, Jamil A, Hoo W, Jauniaux E, Jurkovic D. Efficacy and
safety of a clinical protocol for expectant management of selected women
diagnosed with a tubal ectopic pregnancy. Ultrasound Obstet Gynecol. 2013
Jul;42(1):102-7. doi: 10.1002/uog.12401. Epub 2013 May 27. PMID: 23303651.
24: Naftalin J, Hoo W, Pateman K, Mavrelos D, Holland T, Jurkovic D. How common
is adenomyosis? A prospective study of prevalence using transvaginal ultrasound
in a gynaecology clinic. Hum Reprod. 2012 Dec;27(12):3432-9. doi:
10.1093/humrep/des332. Epub 2012 Sep 20. PMID: 23001775.
25: Holland TK, Hoo WL, Mavrelos D, Saridogan E, Cutner A, Jurkovic D.
Reproducibility of assessment of severity of pelvic endometriosis using
transvaginal ultrasound. Ultrasound Obstet Gynecol. 2013 Feb;41(2):210-5. doi:
10.1002/uog.11216. PMID: 22745055.
26: Naftalin J, Hoo W, Nunes N, Mavrelos D, Nicks H, Jurkovic D. Inter- and
intraobserver variability in three-dimensional ultrasound assessment of the
endometrial-myometrial junction and factors affecting its visualization.
Ultrasound Obstet Gynecol. 2012 May;39(5):587-91. doi: 10.1002/uog.10133. PMID:
22045594.
27: Pavlakis K, Messini I, Papadimitriou CA, Zagouri F, Yiannou P, Mavrelos D,
Panoskaltis T. Tumor dissemination after laparoscopic surgery for an unsuspected
endometrial stromal tumor. Eur J Gynaecol Oncol. 2011;32(3):362-3. PMID:
21797138.
28: Mavrelos D, Naftalin J, Hoo W, Ben-Nagi J, Holland T, Jurkovic D.
Preoperative assessment of submucous fibroids by three-dimensional saline
contrast sonohysterography. Ultrasound Obstet Gynecol. 2011 Sep;38(3):350-4.
doi: 10.1002/uog.9049. Epub 2011 Aug 10. PMID: 21584888.
29: Ben-Nagi J, Miell J, Mavrelos D, Naftalin J, Lee C, Jurkovic D. Endometrial
implantation factors in women with submucous uterine fibroids. Reprod Biomed
Online. 2010 Nov;21(5):610-5. doi: 10.1016/j.rbmo.2010.06.039. Epub 2010 Sep 28.
PMID: 20880745.
30: Mavrelos D, Ben-Nagi J, Davies A, Lee C, Salim R, Jurkovic D. The value of
pre-operative treatment with GnRH analogues in women with submucous fibroids: a
double-blind, placebo-controlled randomized trial. Hum Reprod. 2010
Sep;25(9):2264-9. doi: 10.1093/humrep/deq188. Epub 2010 Jul 27. PMID: 20663795.
31: Hoo WL, Yazbek J, Holland T, Mavrelos D, Tong EN, Jurkovic D. Expectant
management of ultrasonically diagnosed ovarian dermoid cysts: is it possible to
predict outcome? Ultrasound Obstet Gynecol. 2010 Aug;36(2):235-40. doi:
10.1002/uog.7610. PMID: 20201114.
32: Mavrelos D, Ben-Nagi J, Holland T, Hoo W, Naftalin J, Jurkovic D. The
natural history of fibroids. Ultrasound Obstet Gynecol. 2010 Feb;35(2):238-42.
doi: 10.1002/uog.7482. PMID: 20069541.
33: Day A, Sawyer E, Mavrelos D, Tailor A, Helmy S, Jurkovic D. Use of serum
progesterone measurements to reduce need for follow-up in women with pregnancies
of unknown location. Ultrasound Obstet Gynecol. 2009 Jun;33(6):704-10. doi:
10.1002/uog.6380. PMID: 19444818.
34: Mavrelos D, Sawyer E, Helmy S, Holland TK, Ben-Nagi J, Jurkovic D.
Ultrasound diagnosis of ectopic pregnancy in the non-communicating horn of a
unicornuate uterus (cornual pregnancy). Ultrasound Obstet Gynecol. 2007
Oct;30(5):765-70. doi: 10.1002/uog.5131. PMID: 17763478.
35: Mavrelos D, Jurkovic D. Polypoid endometrium on three-dimensional saline
contrast sonohysterography. Ultrasound Obstet Gynecol. 2007 Aug;30(2):231-2.
doi: 10.1002/uog.5127. PMID: 17659654.
36: Jurkovic D, Mavrelos D. Catch me if you scan: ultrasound diagnosis of
ectopic pregnancy. Ultrasound Obstet Gynecol. 2007 Jul;30(1):1-7. doi:
10.1002/uog.4077. PMID: 17587215.
37: Konstas AA, Mavrelos D, Korbmacher C. Conservation of pH sensitivity in the
epithelial sodium channel (ENaC) with Liddle's syndrome mutation. Pflugers Arch.
2000 Dec;441(2-3):341-50. doi: 10.1007/s004240000430. PMID: 1
Languages spoken
Greek, French, Spanish
Publications
1: Mavrelos D, Holland TK, O'Donovan O, Khalil M, Ploumpidis G, Jurkovic D,
Khalaf Y. The impact of adenomyosis on the outcome of IVF-embryo transfer. Reprod
Biomed Online. 2017 Jul 29. pii: S1472-6483(17)30347-4. doi:
10.1016/j.rbmo.2017.06.026. [Epub ahead of print] PubMed PMID: 28802706.
2: Mavrelos D, Al Chami A, Talaulikar V, Burt E, Webber L, Ploubidis G, Yasmin E.
Variation in antral follicle counts at different times in the menstrual cycle:
does it matter? Reprod Biomed Online. 2016 Aug;33(2):174-9. doi:
10.1016/j.rbmo.2016.04.012. Epub 2016 May 5. PubMed PMID: 27184084.
3: Jurkovic D, Knez J, Appiah A, Farahani L, Mavrelos D, Ross JA. Surgical
treatment of Cesarean scar ectopic pregnancy: efficacy and safety of
ultrasound-guided suction curettage. Ultrasound Obstet Gynecol. 2016
Apr;47(4):511-7. doi: 10.1002/uog.15857. PubMed PMID: 26764166.
4: Naftalin J, Hoo W, Nunes N, Holland T, Mavrelos D, Jurkovic D. Association
between ultrasound features of adenomyosis and severity of menstrual pain.
Ultrasound Obstet Gynecol. 2016 Jun;47(6):779-83. doi: 10.1002/uog.15798. PubMed
PMID: 26499878.
5: Helmy S, Mavrelos D, Sawyer E, Ben-Nagi J, Koch M, Day A, Jurkovic D. Serum
Human Chorionic Gonadotropin (?- hCG) Clearance Curves in Women with Successfully
Expectantly Managed Tubal Ectopic Pregnancies: A Retrospective Cohort Study. PLoS
One. 2015 Jul 2;10(7):e0130598. doi: 10.1371/journal.pone.0130598. eCollection
2015. PubMed PMID: 26135923; PubMed Central PMCID: PMC4489732.
6: Mavrelos D, Memtsa M, Helmy S, Derdelis G, Jauniaux E, Jurkovic D. ?-hCG
resolution times during expectant management of tubal ectopic pregnancies. BMC
Womens Health. 2015 May 21;15:43. doi: 10.1186/s12905-015-0200-7. PubMed PMID:
25994203; PubMed Central PMCID: PMC4443555.
7: Mavrelos D, Saridogan E. Treatment of endometriosis in women desiring
fertility. J Obstet Gynaecol India. 2015 Feb;65(1):11-6. doi:
10.1007/s13224-014-0652-y. Epub 2015 Jan 22. Review. PubMed PMID: 25737616;
PubMed Central PMCID: PMC4342385.
8: Pateman K, Moro F, Mavrelos D, Foo X, Hoo WL, Jurkovic D. Natural history of
ovarian endometrioma in pregnancy. BMC Womens Health. 2014 Oct 15;14:128. doi:
10.1186/1472-6874-14-128. PubMed PMID: 25315259; PubMed Central PMCID:
PMC4287586.
9: Moro F, Mavrelos D, Pateman K, Holland T, Hoo WL, Jurkovic D. Prevalence of
pelvic adhesions on ultrasound examination in women with a history of Cesarean
section. Ultrasound Obstet Gynecol. 2015 Feb;45(2):223-8. doi: 10.1002/uog.14628.
Epub 2014 Dec 26. PubMed PMID: 25042444.
10: Ludovisi M, Mavrelos D, Jurkovic D. Re: factors affecting visualization of
postmenopausal ovaries: descriptive study from the multicenter United Kingdom
Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Ultrasound Obstet
Gynecol. 2014 May;43(5):600. doi: 10.1002/uog.13321. PubMed PMID: 24789306.
11: Naftalin J, Hoo W, Pateman K, Mavrelos D, Foo X, Jurkovic D. Is adenomyosis
associated with menorrhagia? Hum Reprod. 2014 Mar;29(3):473-9. doi:
10.1093/humrep/det451. Epub 2014 Jan 8. PubMed PMID: 24408315.
12: Holland TK, Cutner A, Saridogan E, Mavrelos D, Pateman K, Jurkovic D.
Ultrasound mapping of pelvic endometriosis: does the location and number of
lesions affect the diagnostic accuracy? A multicentre diagnostic accuracy study.
BMC Womens Health. 2013 Oct 29;13:43. doi: 10.1186/1472-6874-13-43. PubMed PMID:
24165087; PubMed Central PMCID: PMC3815071.
13: Mavrelos D, Cohen H, Pateman K, Hoo W, Foo X, Jurkovic D. Diagnosis of
uterine vein thrombosis on transvaginal ultrasound. Ultrasound Obstet Gynecol.
2013 Oct;42(4):480-3. doi: 10.1002/uog.12520. Epub 2013 Aug 12. PubMed PMID:
23716379.
14: Pateman K, Mavrelos D, Hoo WL, Holland T, Naftalin J, Jurkovic D.
Visualization of ureters on standard gynecological transvaginal scan: a
feasibility study. Ultrasound Obstet Gynecol. 2013 Jun;41(6):696-701. doi:
10.1002/uog.12468. Epub 2013 May 7. PubMed PMID: 23554048.
15: Mavrelos D, Nicks H, Jamil A, Hoo W, Jauniaux E, Jurkovic D. Efficacy and
safety of a clinical protocol for expectant management of selected women
diagnosed with a tubal ectopic pregnancy. Ultrasound Obstet Gynecol. 2013
Jul;42(1):102-7. doi: 10.1002/uog.12401. Epub 2013 May 27. PubMed PMID: 23303651.
16: Naftalin J, Hoo W, Pateman K, Mavrelos D, Holland T, Jurkovic D. How common
is adenomyosis? A prospective study of prevalence using transvaginal ultrasound
in a gynaecology clinic. Hum Reprod. 2012 Dec;27(12):3432-9. doi:
10.1093/humrep/des332. Epub 2012 Sep 20. PubMed PMID: 23001775.
17: Holland TK, Hoo WL, Mavrelos D, Saridogan E, Cutner A, Jurkovic D.
Reproducibility of assessment of severity of pelvic endometriosis using
transvaginal ultrasound. Ultrasound Obstet Gynecol. 2013 Feb;41(2):210-5. doi:
10.1002/uog.11216. PubMed PMID: 22745055.
18: Naftalin J, Hoo W, Nunes N, Mavrelos D, Nicks H, Jurkovic D. Inter- and
intraobserver variability in three-dimensional ultrasound assessment of the
endometrial-myometrial junction and factors affecting its visualization.
Ultrasound Obstet Gynecol. 2012 May;39(5):587-91. doi: 10.1002/uog.10133. PubMed
PMID: 22045594.
19: Pavlakis K, Messini I, Papadimitriou CA, Zagouri F, Yiannou P, Mavrelos D,
Panoskaltis T. Tumor dissemination after laparoscopic surgery for an unsuspected
endometrial stromal tumor. Eur J Gynaecol Oncol. 2011;32(3):362-3. PubMed PMID:
21797138.
20: Mavrelos D, Naftalin J, Hoo W, Ben-Nagi J, Holland T, Jurkovic D.
Preoperative assessment of submucous fibroids by three-dimensional saline
contrast sonohysterography. Ultrasound Obstet Gynecol. 2011 Sep;38(3):350-4. doi:
10.1002/uog.9049. Epub 2011 Aug 10. PubMed PMID: 21584888.
21: Ben-Nagi J, Miell J, Mavrelos D, Naftalin J, Lee C, Jurkovic D. Endometrial
implantation factors in women with submucous uterine fibroids. Reprod Biomed
Online. 2010 Nov;21(5):610-5. doi: 10.1016/j.rbmo.2010.06.039. Epub 2010 Sep 28.
PubMed PMID: 20880745.
22: Mavrelos D, Ben-Nagi J, Davies A, Lee C, Salim R, Jurkovic D. The value of
pre-operative treatment with GnRH analogues in women with submucous fibroids: a
double-blind, placebo-controlled randomized trial. Hum Reprod. 2010
Sep;25(9):2264-9. doi: 10.1093/humrep/deq188. Epub 2010 Jul 27. PubMed PMID:
20663795.
23: Hoo WL, Yazbek J, Holland T, Mavrelos D, Tong EN, Jurkovic D. Expectant
management of ultrasonically diagnosed ovarian dermoid cysts: is it possible to
predict outcome? Ultrasound Obstet Gynecol. 2010 Aug;36(2):235-40. doi:
10.1002/uog.7610. PubMed PMID: 20201114.
24: Mavrelos D, Ben-Nagi J, Holland T, Hoo W, Naftalin J, Jurkovic D. The natural
history of fibroids. Ultrasound Obstet Gynecol. 2010 Feb;35(2):238-42. doi:
10.1002/uog.7482. PubMed PMID: 20069541.
25: Day A, Sawyer E, Mavrelos D, Tailor A, Helmy S, Jurkovic D. Use of serum
progesterone measurements to reduce need for follow-up in women with pregnancies
of unknown location. Ultrasound Obstet Gynecol. 2009 Jun;33(6):704-10. doi:
10.1002/uog.6380. PubMed PMID: 19444818.
26: Mavrelos D, Sawyer E, Helmy S, Holland TK, Ben-Nagi J, Jurkovic D. Ultrasound
diagnosis of ectopic pregnancy in the non-communicating horn of a unicornuate
uterus (cornual pregnancy). Ultrasound Obstet Gynecol. 2007 Oct;30(5):765-70.
PubMed PMID: 17763478.
27: Mavrelos D, Jurkovic D. Polypoid endometrium on three-dimensional saline
contrast sonohysterography. Ultrasound Obstet Gynecol. 2007 Aug;30(2):231-2.
PubMed PMID: 17659654.
28: Jurkovic D, Mavrelos D. Catch me if you scan: ultrasound diagnosis of ectopic
pregnancy. Ultrasound Obstet Gynecol. 2007 Jul;30(1):1-7. Review. PubMed PMID:
17587215.
29: Konstas AA, Mavrelos D, Korbmacher C. Conservation of pH sensitivity in the
epithelial sodium channel (ENaC) with Liddle's syndrome mutation. Pflugers Arch.
2000 Dec;441(2-3):341-50. PubMed PMID: 11211122.