Photo of Dr Marco Orlandi

Dr Marco Orlandi

Email:

Location:

  • Royal National ENT and Eastman Dental Hospitals

GMC/GDC number:

187799

Professional background

Dr Marco Orlandi was awarded a degree in Dentistry in 2007 at the University of Rome “Tor Vergata” and has subsequently completed a PhD and a specialist training in Periodontology at UCLH/UCL.

He is a member of the Royal College of Surgeons of Edinburgh and England and national and international societies in periodontology.

Specialties

Research interests

The link between periodontitis and general health and more specifically the impact that the inflammatory process associated with periodontitis might have on chronic inflammatory conditions such as cardiometabolic, rheumatic and neurodegenerative diseases.

Languages spoken

Italian, Spanish

Publications

  • Luthra, S., Orlandi, M., Hussain, S. B., Leira, Y., Botelho, J., Machado, V., . . . D'Aiuto, F. (2023). Treatment of Periodontitis and C-Reactive Protein: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Journal of Clinical Periodontology. doi:10.1111/jcpe.13709
  • Papi, P., Pranno, N., Di Murro, B., Pompa, G., Polimeni, A., Letizia, C., . . . D'Aiuto, F. (2022). Association between subclinical atherosclerosis and oral inflammation: A cross-sectional study. Journal of Periodontology. doi:10.1002/JPER.22-0026
  • Leira, Y., Cho, H., Marletta, D., Orlandi, M., Diz, P., Kumar, N., & D’Aiuto, F. (2022). Complications and treatment errors in periodontal therapy in medically compromised patients. Periodontology 2000. doi:10.1111/prd.12444
  • Orlandi, M., Munoz Aguilera, E., Marletta, D., Petrie, A., Suvan, J., & D'Aiuto, F. (2022). Impact of the treatment of periodontitis on systemic health and quality of life: A systematic review. JOURNAL OF CLINICAL PERIODONTOLOGY. doi:10.1111/jcpe.13554
  • Luthra, S., Orlandi, M., Leira, Y., Bokre, D., Marletta, D., Rotundo, R., . . . D'Aiuto, F. (2022). Invasive Dental Treatment and Acute Vascular Events: A Systematic Review and Meta-Analysis. Journal of Clinical Periodontology. doi:10.1111/jcpe.13600
  • Hussain, S., Leira, Y., Zehra, S., Botelho, J., Machado, V., Ciurtin, C., . . . Orlandi, M. (2022). Periodontitis and Systemic Lupus Erythematosus: A systematic review and meta-analysis. Journal of Periodontal Research. doi:10.1111/jre.12936
  • Muñoz Aguilera, E., Suvan, J., Orlandi, M., Miró Catalina, Q., Nart, J., & D'Aiuto, F. (2021). Association Between Periodontitis and Blood Pressure Highlighted in Systemically Healthy Individuals: Results From a Nested Case-Control Study. Hypertension, HYPERTENSIONAHA12016790. doi:10.1161/HYPERTENSIONAHA.120.16790
  • Botelho, J., Machado, V., Hussain, S. B., Zehra, S. A., Proença, L., Orlandi, M., . . . D'Aiuto, F. (2021). Periodontitis and circulating blood cell profiles: a systematic review and meta-analysis. Experimental Hematology. doi:10.1016/j.exphem.2020.10.001
  • Orlandi, M., Masi, S., Bhowruth, D., Leira Feijoo, Y., Georgiopoulos, G., Yellon, D., . . . D'Aiuto, F. (2021). Remote ischemic preconditioning (RIPC) protects against endothelial dysfunction in a human model of systemic inflammation: a randomized clinical trial. Arteriosclerosis, Thrombosis and Vascular Biology. doi:10.1161/ATVBAHA.121.316388
  • Machado, V., Botelho, J., Escalda, C., Hussain, S. B., Luthra, S., Mascarenhas, P., . . . D'Aiuto, F. (2021). Serum C-Reactive Protein and Periodontitis: A Systematic Review and Meta-Analysis. Frontiers in Immunology, 12, 70643. doi:10.3389/fimmu.2021.706432
  • Leow, N., Orlandi, M., Suvan, J., Gkranias, N., Tsakos, G., Donos, N., . . . D'Aiuto, F. (2021). Treatment of periodontitis and patient-reported oral health outcomes in diabetes. Presented at: 2021 IADR/ AADR/ CADR General Session & Exhibition.
  • Muñoz Aguilera, E., Leira, Y., Miró Catalina, Q., Orlandi, M., Czesnikiewicz-Guzik, M., Guzik, T. J., . . . D'Aiuto, F. (2020). Is systemic inflammation a missing link between periodontitis and hypertension? Results from two large population‐based surveys. Journal of Internal Medicine. doi:10.1111/joim.13180
  • Hussain, S. B., Botelho, J., Machado, V., Zehra, S. A., Mendes, J. J., Ciurtin, C., . . . Aiuto, F. D. (2020). Is there a bidirectional association between rheumatoid arthritis and periodontitis? A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism. doi:10.1016/j.semarthrit.2020.01.009 · Orlandi, M., D'Aiuto, F., Ciurtin, C., & Porter, S. (2020). Lupus and the Mouth. Lupus Diagnosis and Treatment. Lupus UK.
  • Orlandi, M., Hussain, S., Botelho, J., Machado, V., Leira, Y., Buti, J., . . . D'Aiuto, F. (n.d.). Periodontal Status In Systemic Lupus Erythematosus: A Systematic Review With Meta-Analysis. Presented at: 2020 IADR/AADR/CADR General Session.
  • Orlandi, M., Graziani, F., & D'Aiuto, F. (2020). Periodontal therapy and cardiovascular risk. Periodontology 2000, 83 (1), 107-124. doi:10.1111/prd.12299 · Leira, Y., Carballo, Á., Orlandi, M., Aldrey, J. M., Pías-Peleteiro, J. M., Moreno, F., . . . Blanco, J. (2020). Periodontitis and Systemic Markers of Neurodegeneration. A case-control study. Journal of Clinical Periodontology. doi:10.1111/jcpe.13267
  • Muñoz Aguilera, E., Suvan, J., Buti, J., Czesnikiewicz-Guzik, M., Barbosa Ribeiro, A., Orlandi, M., . . . D’Aiuto, F. (2020). Periodontitis is associated with hypertension: a systematic review and meta-analysis. Cardiovascular Research. doi:10.1093/cvr/cvz201
  • Moreno Sancho, F., Leira, Y., Orlandi, M., Buti, J., Giannobile, W. V., & D'Aiuto, F. (2019). Cell-Based Therapies for Alveolar Bone and Periodontal Regeneration: Concise Review. Stem Cells Transl Med. doi:10.1002/sctm.19-0183
  • Leira, Y., Pozo-Rosich, P., Torres-Ferrús, M., Orlandi, M., Láinez, J. M., Álvaro, L. C., . . . D’Aiuto, F. (2019). Self-reported periodontitis and migraine: results from a multicenter, cross-sectional survey in Spain. Odontology. doi:10.1007/s10266-019-00430-w · Munoz Aguilera, E., Rotundo, R., Orlandi, M., & Leira Feijoo, Y. (2019). Tratamiento de recesiones unitarias de clase III de Miller en el maxilar anterior. Periodoncia Clínica.
  • Leira, Y., Blanco, J., Buti, J., Orlandi, M., Pozo-rosich, P., Lainez, J. M., . . . D'Aiuto, F. (2018). Association of the Migraine With Severe Periodontitis. Presented at: 2018 IADR/PER General Session.

  • Hussain, S. H., Leira, Y., Orlandi, M., Buti, J., Ciurtin, C., & D'Aiuto, F. (2018). Does Systemic Lupus Erythematosus Affect the Severity of Periodontitis? A Systematic Review and Meta-analysis. Presented at: 2018 IADR/PER General Session.

  • Masi, S., Orlandi, M., Parkar, M., Bhowruth, D., Kingston, I., O'Rourke, C., . . . Deanfield, J. (2018). Mitochondrial oxidative stress, endothelial function and metabolic control in patients with type II diabetes and periodontitis: A randomised controlled clinical tria. International Journal of Cardiology, 271, 263-268. doi:10.1016/j.ijcard.2018.05.019

  • Orlandi, M., Bhowruth, D., Buti, J., Moreno Sancho, F., Suvan, J., Curra, M. C., & D'Aiuto, F. (2018). Modulation of Acute Gingival Inflammation by Sodium-Bicarbonate. An experimental Gingivitis Model. Presented at: 2018 IADR/PER General Session.

  • Orlandi, M., Guinto, J., Bakshi, J., Cotton, A., Wilton, J., Bernstein, B., . . . Ciurtin, C. (2018). Prevalence of Periodontitis in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematous. Presented at: British Society of Rheumatology.

  • D'Aiuto, F., Gkranias, N., Bhowruth, D., Khan, T., Orlandi, M., Suvan, J., . . . Deanfield, J. E. (2018). Systemic effects of periodontitis treatment in patients with type 2 diabetes: a 12 month, single-centre, investigator-masked, randomised trial. LANCET DIABETES & ENDOCRINOLOGY, 6 (12), 954-965. doi:10.1016/S2213-8587(18)30038-X

  • Sofat, N., Rutter-Locher, Z., Fuggle, N., Orlandi, M., & D'Aiuto, F. (2017). Periodontal Disease and Autoimmunity: What We Have Learned from Microbiome Studies in Rheumatology. Periodontitis - A Useful Reference. intechopen.

  • Orlandi, M. (2016). The impact of periodontal infection and its treatment on systemic inflammation, oxidative stress and endothelium integrity (Doctoral dissertation). UCL.

  • Graziani, F., Cei, S., Orlandi, M., Gennai, S., Gabriele, M., Filice, N., . . . D'Aiuto, F. (2015). Acute-phase response following full-mouth versus quadrant non-surgical periodontal treatment: A randomized clinical trial. Journal of Clinical Periodontology, 42 (9), 843-852. doi:10.1111/jcpe.12451

  • Artese, H. P. C., Foz, A. M., Rabelo, M. D. S., Gomes, G. H., Romito, G. A., Orlandi, M., . . . D Aiuto, F. (2015). Periodontal therapy and systemic inflammation in type 2 diabetes mellitus: A meta-analysis. PLoS ONE, 10 (5). doi:10.1371/journal.pone.0128344

  • Orlandi, M., Suvan, J., Petrie, A., Donos, N., Masi, S., Hingorani, A., . . . D'Aiuto, F. (2014). Association between periodontal disease and its treatment, flow-mediated dilatation and carotid intima-media thickness: A systematic review and meta-analysis. Atherosclerosis, 17 (236), 39-46.

  • Masi, S., Gkranias, N., Li, K., Salpea, K. D., Parkar, M., Orlandi, M., . . . D'Aiuto, F. (2014). Association between short leukocyte telomere length, endotoxemia, and severe periodontitis in people with diabetes: a cross-sectional survey. Diabetes Care, 37 (4), 1140-1147. doi:10.2337/dc13-2106 

  • D'Aiuto, F., Orlandi, M., & Gunsolley, J. C. (2013). Evidence that periodontal treatment improves biomarkers and CVD outcomes. Journal of Clinical Periodontology, 40, S85-S105. doi:10.1111/jcpe.12061

  • D’Aiuto, F., Orlandi, M., & Gunsolley, J. C. (2013). Evidence that periodontal treatment improves biomarkers and CVD outcomes. Journal of Periodontology, 84 (4S). doi:10.1902/jop.2013.134007

  • Rutter-Locher, Z., Fuggle, N., Orlandi, M., Kaul, A., D'Aiuto, F., & Sofat, N. (n.d.). Periodontal disease in systemic lupus erythematosus: is there a link?