Dr Catherine Mummery
Telephone:
Location:
- National Hospital for Neurology and Neurosurgery
GMC/GDC number:
3504590
Professional background
Dr Cath Mummery has been a consultant neurologist since 2002 and leads the cognitive disorders service at the National Hospital for Neurology and Neurosurgery. She studied medicine at UCH, trained in neurology at NHNN and Kings College Hospital, and gained a PhD in cognitive neurology at the Wellcome Department of Functional Imaging, UCL.
She is head of novel therapeutics at the Dementia Research Centre, UCL and has been senior investigator on over 20 early phase drug trials of disease modifying agents in dementias including genetic forms of Alzheimer’s disease and frontotemporal dementia. She is deputy director for the Leonard Wolfson Experimental Neurology Centre at NHNN, a unit dedicated to early phase trials in neurodegeneration.
She was elected to the executive of the Association of British neurologists as services chair in 2017 and also works closely with the Royal College of Physicians, sitting on the medical specialties board and chairing the joint clinical neurosciences committee. As deputy director of the NHSE Neurosciences Clinical Reference Group, she is closely involved in work to enhance neurology care for patients.
Research interests
- Early phase clinical trials in dementia and those at risk of dementia
- Enhancing patient care by integrated care networks in those with unusual forms of dementia
Publications
Mummery CJ, Patterson K, Hodges JR, Wise RJS. Generating ‘tiger’ as an animal name or a word beginning with T: differences in brain activation Proc R Soc Lond B (1996), 263, 989-995.
Mummery CJ, Patterson K, Hodges JR, and Price CJ. Functional neuroanatomy of the semantic system: - divisible by what? J Cog Neurosci (1998), 10, 6, 766-777.
Mummery CJ, Patterson K, Wise RJS, Price CJ, Hodges JR. Disrupted temporal lobe connections in semantic dementia. Brain (1999), 22, 1, 101-113.
Mummery CJ, Shallice T, Price CJ. Mechanisms of semantic priming - insights from functional imaging. Neuroimage (1999) 5(9) 516-525.
Mummery CJ, Scott SK, Ashburner J, and Wise RJS. Functional neuroimaging of speech perception in normals and patients. J Acoustic Soc Am (1999), 106(1), 449-57.
Maguire EA and Mummery CJ. Differential modulation of a common memory retrieval network revealed by PET. Hippocampus (1999) 9, 54-61.
Price CJ, Mummery CJ, Moore CJ, Frackowiak RSJ, Friston KJ. Combining functional imaging and neuropsychology to delineate necessary and sufficient neural systems J Cog Neurosci. (1999) 11(4), 371-382.
Mummery CJ, Patterson K, Price CJ, Frackowiak RSJ, Hodges JR. A voxel-based morphometry study of semantic dementia: The relation of temporal lobe atrophy to cognitive deficit. Ann Neurol. (2000), 47(1), 36-45.
Wise RJS, Howard D, Mummery CJ, Fletcher P, Leff A, Buchel C, Scott SK. Noun imageability and the temporal lobes. Neuropsychologia (2000), 38(7), 985-94.
Maguire EA, Mummery CJ, Buchel C. Effective connectivity dissociates distinct memory pathways within the temporal lobe. Hippocampus (2000) 10(4):475-82
Wise RJ, Scott SK, Blank SC, Mummery CJ, Murphy K, Warburton EA. Separate neural subsystems within 'Wernicke's area'. Brain. (2001) Jan;124(Pt 1):83-95.
Maguire EA, Henson RNA, Mummery CJ, Frith CD. Activity in prefrontal cortex, not hippocampus, varies parametrically with the increasing remoteness of memories. Neuroreport (2001) 12(3), 441-444.
Uta Noppeney, Karalyn Patterson, Lorraine K. Tyler, Helen Moss, Emmanuel A. Stamatakis, Peter Bright, Cath Mummery and Cathy J. Price. Temporal lobe lesions and semantic impairment: a comparison of herpes simplex virus encephalitis and semantic dementia. Brain 2007 130(4):1138-1147
Knight WD, Kennedy J, Mead S, Rossor MN, Beck J, Collinge J, Mummery C. A novel presenilin 1 deletion (p.L166del) associated with early onset familial Alzheimer's disease. Eur J Neurol. 2007 Jul;14(7):829-31.
Omar R, Sampson EL, Loy CT, Mummery CJ, Fox NC, Rossor MN, Warren JD. Delusions in frontotemporal lobar degeneration. J Neurol. 2009 Apr;256(4):600-7.
Rossor MN, Fox NC, Mummery CJ, Schott JM, Warren JD. The diagnosis of young onset dementia. Lancet Neurology Aug 2010; 9:8, 793-806
Livingston G, Barber J, Rapaport P, Knapp M, Griffin M, King D, Livingston D, Mummery C, Walker Z, Hoe J, Sampson EL, Cooper C. Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial. BMJ. 2013 Oct 25;347:f6276.
Beck J, Pittman A, Adamson G, Campbell T, Kenny J, Houlden H, Rohrer JD, de Silva R, Shoai M, Uphill J, Poulter M, Hardy J, Mummery CJ, Warren JD, Schott JM, Fox NC, Rossor MN, Collinge J, Mead S. Validation of next-generation sequencing technologies in genetic diagnosis of dementia. Neurobiol Aging. 2014 Jan;35(1):261-5.
Fletcher PD, Nicholas JM, Shakespeare TJ, Downey LE, Golden HL, Agustus JL, Clark CN, Mummery CJ, Schott JM, Crutch SJ, Warren JD. Physiological phenotyping of dementias using emotional sounds Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. Volume 1, Issue 2, June 2015, Pages 170–178
Golden, H.L., Nicholas, J.M., Yong, K.X., Downey, L.E., Schott, J.M., Mummery, C.J., Crutch, S.J. and Warren, J.D., 2015. Auditory spatial processing in Alzheimer’s disease. Brain, 138(1), pp.189-202.
Fletcher PD, Nicholas JM, Shakespeare TJ, Downey Downey LE, Golden HL, Agustus JL, Clark CN, Mummery CJ, Schott JM, Crutch SJ, Warren JD. Dementias show differential physiological responses to salient sounds. Front. Behav. Neurosci., 24 March 2015
Golden, H.L., Downey, L.E., Fletcher, P.D., Mahoney, C.J., Schott, J.M., Mummery, C.J., Crutch, S.J. and Warren, J.D., 2015. Identification of environmental sounds and melodies in syndromes of anterior temporal lobe degeneration. Journal of the neurological sciences, 352(1), pp.94-98.
Ahmed, R.M., Murphy, E., Davagnanam, I., Parton, M., Schott, J.M., Mummery, C.J., Rohrer, J.D., Lachmann, R.H., Houlden, H., Fox, N.C. and Chataway, J., 2013. A practical approach to diagnosing adult onset leucodystrophies. Journal of Neurology, Neurosurgery & Psychiatry, pp.jnnp-2013.
Clark, C.N., Nicholas, J.M., Gordon, E., Golden, H.L., Cohen, M.H., Woodward, F.J., Macpherson, K., Slattery, C.F., Mummery, C.J., Schott, J.M. and Rohrer, J.D., 2015. Altered sense of humor in dementia. Journal of Alzheimer's Disease, 49(1), pp.111-119.
Weston, P.S., Paterson, R.W., Dickson, J., Barnes, A., Bomanji, J.B., Kayani, I., Lunn, M.P., Mummery, C.J., Warren, J.D., Rossor, M.N. and Fox, N.C., 2016. Diagnosing Dementia in the Clinical Setting: Can Amyloid PET Provide Additional Value Over Cerebrospinal Fluid?. Journal of Alzheimer's Disease, (Preprint), pp.1-6.
Bond, R.L., Downey, L.E., Weston, P.S., Slattery, C.F., Clark, C.N., Macpherson, K., Mummery, C.J. and Warren, J.D., 2016. Processing of self versus non-self in Alzheimer’s disease. Frontiers in human neuroscience, 10.
Fletcher, P.D., Nicholas, J.M., Downey, L.E., Golden, H.L., Clark, C.N., Pires, C., Agustus, J.L., Mummery, C.J., Schott, J.M., Rohrer, J.D. and Crutch, S.J., 2016. A physiological signature of sound meaning in dementia. Cortex, 77, pp.13-23.
Agustus, J.L., Clark, C.N., Golden, H.L., Slattery, C.F., Fletcher, P.D., Cohen, M.H., Downey, L.E., Mummery, C.J., Rossor, M.N., Schott, J.M. and Mead, S., 2015. Dementia and music: fMRI signatures of molecular nexopathies. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 11(7), p.P528.
Clark, C.N., Nicholas, J.M., Henley, S.M., Downey, L.E., Woollacott, I.O., Golden, H.L., Fletcher, P.D., Mummery, C.J., Schott, J.M., Rohrer, J.D. and Crutch, S.J., 2015. Humour processing in frontotemporal lobar degeneration: A behavioural and neuroanatomical analysis. Cortex, 69, pp.47-59.
Golden, H.L., Agustus, J.L., Goll, J.C., Downey, L.E., Mummery, C.J., Schott, J.M., Crutch, S.J. and Warren, J.D., 2015. Functional neuroanatomy of auditory scene analysis in Alzheimer's disease. NeuroImage: Clinical, 7, pp.699-708.
Hardy, C.J., Marshall, C.R., Golden, H.L., Clark, C.N., Mummery, C.J., Griffiths, T.D., Bamiou, D.E. and Warren, J.D., 2016. Hearing and dementia. Journal of Neurology, pp.1-16.
Atkinson, J., Denmark, T., Marshall, J., Mummery, C. and Woll, B., 2015. Detecting Cognitive Impairment and Dementia in Deaf People: The British Sign Language Cognitive Screening Test. Archives of Clinical Neuropsychology, (2016) 31 (8): 855-867
Lynch D.S., Brandão de Paiva A.R., Zhang W.J., Bugiardini E., Freua F., Lucato L.T., Macedo-Souza L.I., Lakhmann R., Kinsella J.A., Merwick A., Rossor A.M., Bajaj N., Herron B., McMonagle P., Morrison P.J., Hughes D., Pittman A., Laurà M., Reilly M.M., Warren J.D., Mummery C.J., Schott J.M., Adams M., Fox N.C. Murphy E., Davagnanam I., Kok F., Chataway C., Houlden H.. Clinical and genetic characterization of leukoencephalopathies in adults. Brain. 2017 May; 140(5): 1204–1211.
Marshall C.R., Hardy C.J.D., Russell L.L., Clark C.C., Bond R.L., Dick K.M., Brotherhood E.V., Mummery C.J., Schott J.M., Rohrer J.D., Kilner J.K., Warren J.D,. Motor signatures of emotional reactivity in frontotemporal dementia. Scientific Reports 8, 1030 (2018)
Magdalinou N.K., Golden H.L., Nicholas J.M., Witoonpanich P., Mummery C.J., Morris H.R., Djamshidian A., Warner T.T., Warrington E.K., Lees A.J. & Warren J.D. (2018) Verbal adynamia in parkinsonian syndromes: behavioral correlates and neuroanatomical substrate, Neurocase, 24:4, 204-212.
Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR Jr, Farlow MR, Salloway S, Snider BJ, Berman SB, Roberson ED, Brosch J, Jimenez-Velazques I, van Dyck CH, Galasko D, Yuan SH, Jayadev S, Honig LS, Gauthier S, Hsiung GR, Masellis M, Brooks WS, Fulham M, Clarnette R, Masters CL, Wallon D, Hannequin D, Dubois B, Pariente J, Sanchez-Valle R, Mummery C, Ringman JM, Bottlaender M, Klein G, Milosavljevic-Ristic S, McDade E, Xiong C, Morris JC, Bateman RJ, Benzinger TLS. Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies. Alzheimers Dement (Amst). 2019 Feb 22;11:180-190.
Shribman S, Alexander SK, Zarkali A, Warner T, Pereira AC, Hughes5 TA, Mummery CJ. Training in neurology: lessons learnt. Practical Neurology Published Online First: 13 May 2019. doi: 10.1136/practneurol-2018-002129
Slattery CF, Agustus JL, Paterson RW, McCallion O, Foulkes AJM, Macpherson K, Carton AM Harding E, Golden HL, Jaisin K, Mummery CJ, Schott JM, Warren JD. The functional neuroanatomy of musical memory in Alzheimer's disease (2019) Cortex, vol 115, 357-70.
Miki Y, Ling H, Crampsie S, Mummery CJ, Rohrer JD, Jaunmuktane Z, Lashley T, Holton JL. Corticospinal tract degeneration and temporal lobe atrophy in frontotemporal lobar degeneration TDP-43 type C pathology Neuropathology and Applied Neurobiology (2019) doi: 10.1111/nan.12582
Fuller G, Connolly M, Mummery C, Williams A. GETTING IT RIGHT FIRST TIME. GIRFT Neurology Methodology and Initial Summary of Regional Data (2019). Available at https://gettingitrightfirsttime.co.uk/girft-methodology/ (accessed October 2019)
Harris MJ, Atkinson JR, Judd K, Bergson M, Mummery CJ., Assessing Deaf patients in the neurology clinic
Practical Neurology Published Online First: 22 November 2019. doi: 10.1136/practneurol-2019-002422
Livingston G, Manela M, O’Keefe Aidan, Rapaport P, Cooper C, Knapp M, King D, Romeo R, Walker Z, Hoe J, Mummery C and Barber J. Clinical effectiveness of the START (STrAtegies for RelaTives) psychological intervention for family carers and the effects on the cost of care for people with dementia: 6-year follow-up of a randomised controlled trial (2020) B. J Pyschiatry vol 216 (1); 35-42