Photo of Dr Aisling Carr

Dr Aisling Carr

Email:

Location:

  • National Hospital for Neurology and Neurosurgery

GMC/GDC number:

6075820

Professional background

Dr Carr sees patients with all types of neurological disease. Her general outpatient clinic is on a Tuesday afternoon and is open to NHS e-Referral Service (formally Choose and Book referrals) referrals.

Her specialist clinical and research interests are in the inflammatory neuropathies, particularly CIDP, vasculitis and paraproteinaemic neuropathies and neurological complications of checkpoint inhibitor chemotherapy. Her outpatient practice as part of the Peripheral Nerve Service in the MRC Centre for Neuromuscular Disease at the National Hospital covers all inflammatory neuropathies, with multidisciplinary support from neurophysiologists, physiotherapists and clinical nurse specialists.

Dr Carr runs the neuromuscular intravenous immunoglobulin (IVIg) and immunosuppression monitoring service which is responsible for safe, optimal management of neuromuscular patients with inflammatory peripheral nervous system diseases. A limited number of appointments are open to choose and book referral for patients with peripheral nerve disease. Please contact the secretary for more details if required.

Specialties

Research interests

Inflammatory neuropathy, acquired and genetic neuropathy, neuromuscular disease, general neurology

Languages spoken

French, Italian

Publications

  • Keddie S, J UK epidemiological and cohort study demonstrates no association between COVID-19 infection and Guillain-Barré Syndrome. Submitted Brain July 2020
  • H Manji, AS Carr, W Brownlee, MJ Lunn. Neurology in the time of covid-19. JNNP = accepted April 2020
  • Mahima Kapoor; Mary M Reilly; Hadi Manji; Michael P Lunn; AS Carr. Dramatic clinical response to ultra-high dose IVIg in otherwise treatment resistant inflammatory neuropathies. International Journal of Neuroscience – accepted August 2020
  • Li, S Brandner, Zane Jaunmktane, Gary Hotton, Kate Cwynarski, C McNamara, Sachit Shah, MP Lunn, AS Carr. Prolonged diagnostic delay in a case of T-cell neurolymphomatosis. BMJ Case Rep. 2019 Dec 29;12(12).
  • S Keddie, A Nagendran, T Cox, Kapoor M, Bomsztyk J, Z Jaunmuktane, S Brandner, H Manji, JH Rees, Ramsay AD, A Rossor, MM Reilly, S D’Sa, AS Carr, MP Lunn. Peripheral nerve neurolymphomatosis; 12 histopathological cases with deep phenotyping. Accepted: Muscle and Nerve April 2020
  • LV Schottlaender, R Abeti, Z Jaunmuktane, M Soutar, J McKinley, OSwayne, C Bettencourt, AS Carr, P Morrison, R Forbes, D Hughes, Alan Pittman, BKalmar, A Richard-Loendt, P Giunti, JRM de Oliveira, M de Grandis, GV Mc Donnell, S Brandner, M Aurrand-Lions, H Houlden. A novel nonsense mutation in JAM2 causing primary familial brain calcification. Am J Hum Genet. 2020 Mar 5; 106(3): 412–421.
  • S Keddie, D Foldes, F Caimari, SE Baldeweg, J Bomsztyk, OJ Ziff, J Fehmi, A Cerner, Z Jaunmuktane, K Yong, H Manji, AS Carr, S Rinaldi, MM Reilly, SD'Sa, and M P Lunn. The Natural History of POEMS Syndrome: clinical characteristics, risk factors and outcomes. Neurology, 2019.
  • E Bugiardini, AKhan, RPhadke, DLynch, A Cortese, L Feng, QGang, AM. Pittman, JM. Morrow, CTurner, AS Carr, R Quinlivan, ARossor,JHolton, MParton,JC Blake, MM Reilly,H Houlden, E Matthews, MG. Genetic and phenotypic characterisation of inherited myopathies in a tertiary neuromuscular centre. Neuromuscul Disord. 2019 Oct;29(10):747-757.
  • Rodríguez Cruz PM, Cossins J, de Paula Estephan E, Munell F, Selby K, Hirano M, Maroofin R, Mehrjardi MYV, Chow G, Carr AS, Manzur A, Robb S, Munot P, Wei Liu W, Banka S, Fraser H, De Goede C, Zanoteli E, Conti Reed U, Sage A, Gratacos M, Macaya A, Dusl M, Senderek J, Töpf A, Hofer M, Knight R, Ramdas S, Jayawant S, Lochmüller H, Palace J, Beeson D. The clinical spectrum of the congenital myasthenic syndrome resulting from COL13A1 mutations. Brain. 2019 Jun 1;142(6):1547-1560.
  • R Keh, A Kahlil, L Nihoyannopoulos, L Compton, M Kapoor, D Gosal, H Manji, AM Rossor, MM Reilly, MP Lunn, TM Lavin, AS Carr. Routine blood monitoring in maintenance Immunoglobulin treatment of inflammatory neuropathy: is it clinically relevant?. J Neurol Sci. 2019 Oct 25;408:116527.
  • Spain L, Tippu Z, Larkin J, Brown R, Carr AS, Turajlic S. How we treat neurological toxicity from immune checkpoint inhibitors. ESMO Open. 2019 Jul 31;4(Suppl 4):e000540.
  • AS Carr, S Shah, D Choi, J Blake, R Phadke, J Gilbertson, CJ Whelan, A D Wechalekar, JD Gillmore, PN Hawkins, MM Reilly. Spinal stenosis in familial transthyretin amyloidosis. J Neuromuscul Dis. 2019;6(2):267-270
  • M Kapoor, J Spillane, C Englezou, S Sarri-Gonzalez, R Bell, A Rossor, H Manji, MM Reilly, MP Lunn, AS Carr. Thromboembolic risk in long-term IVIg treatment: incidence and risk factors in inflammatory neuropathy patients. Neurology 2020.
  • S Keddie, S D'Sa, D Foldes, A S Carr, MM Reilly, MPT Lunn. POEMS neuropathy: optimising diagnosis and management. Pract Neurol 2018;0: 1-13. doi:10.1136/practneurol-2017-001792.
  • S Keddie, Z Jaunmuktane, S Brandner, S Shah, P Maddison, JH Rees, MG Hanna, MPT Lunn, MM Reilly, AM Rossor, AS Carr. A diagnostic conundrum. Pract Neurol 2018;0:1–6. doi:10.1136/practneurol-2017-001801
  • Ramdharry G, Carr AS, Laura M. Chapter 13: Polyneuropathies. In Lennon, Ramdharry, Verheyden: Physical Management for Neurological Conditions, 2018; 4th Edition, Elsevier, Oxford, UK.
  • Ramdharry G, Carr AS. Chapter 13: Guillain Barre Syndrome. In Lennon, Ramdharry, Verheyden: Pocketbook of Neuro-physiotherapy, 2018; Elsevier, Oxford, UK.
  • Rossor AM*, Carr AS*, Devine H, Pelayo-Negro A, Pareyson D, Shy M, Scherer S, Reilly MM. Peripheral neuropathy in complex inherited diseases: An approach to diagnosis. J Neurol Neurosurg Psychiatry. 2017 Oct;88(10):846-863. doi: 10.1136/jnnp-2016-313960.
  • PJ Tomaselli, AM Rossor, A Horga, AS Carr, P Saveri, G Piscosquito, D Pareyson, MM Laura, JC Blake, R Poh, J Polke, H Houlden, MM. Reilly. Mutations in non-coding regions of GJB1 are a significant cause of X-linked Charcot-Marie-Tooth disease. Neurology. 2017 Apr 11;88(15):1445-1453
  • AS Carr, MRB Evans, S Shah, S Catania, JD Warren, MJ Gleeson, MM Reilly.Focal injury causing tongue hemiasthesia, dysguesia, dysarthria and dysphagia: a case report. Pract Neurol. 2017 Feb 26. pii: practneurol-2016-001491
  • AS Carr, AL Pelayo-Negro, MRB Evans, M Laura, J Blake, C Stancanelli, V Iodice, AD Wechalekar, CJ Whelan, JD Gilmore, PN Hawkins, MM Reilly. A study of the neuropathy associated with Transthyretin Amyloidosis (ATTR) in the UK. J Neurol Neurosurg Psychiatry. 2015 Aug 4. pii: jnnp-2015-310907. doi: 10.1136/jnnp-2015-310907
  • AS Carr. Actual world epidemiology of Myasthenia Gravis (Chapter 2). In Mineo TC, editor. Novel Challenges in Myasthenia Gravis. Nova Science Publishers, Inc.: 2015;
  • AS Carr, JM Polke, AL Pelago, M Laura, B Lecky, J Vaughan, J Rankin, MG Sweeny, H Houlden, MM Reilly.MFN2 deletion founder mutation in the UK population. J Peripher Nerv Syst. 2015 Jun;20(2):67-71. doi: 10.1111/jns.12117.
  • AS Carr, Z Jaunmuktane, D Hutt, S Brandner, J Holton, J Blake, C Whelan, A Wechaleka, J Gilmore, P Hawkins, MM Reilly . Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy.. Neuromuscul Disord. 2015 Jun;25(6):511-5. doi: 10.1016/j.nmd.2015.02.001
  • AL. Pelayo-Negro, AS Carr, M Laura, M Skorupinska, MM Reilly. An observational study of asymmetry in CMT1A.: J Neurol Neurosurg Psychiatry. 2014 Oct 13. pii: jnnp-2014-309096. doi: 10.1136/jnnp-2014-309096.
  • González, MI Leite, P Waters, M Woodhall, E 9.92 Coutinho, B Balint, B Lang, P Pettingill, AS Carr, U Sheerin, R Press ,MP Lunn, MLim, PMaddison, HM Meinck, W Vandenberghe, AVincent. Glycine receptor antibodies in PERM and related syndromes:characteristics, clinical features and outcomes. Brain. 2014 Aug;137(Pt 8):2178-92.
  • AS Carr, AI Hoetizaur, R Kee, M Kinney, J Campbell, A Hutchinson, GV McDonnell. Acute Neuromuscular respiratory failure: a population based study in Northern Ireland. Postgrad Med J. 2014 Apr;90(1062):201-4.
  • Armangue T, Titulaer MJ, Sabater L, Pardo-Moreno J, Gresa-Arribas N, Barbero-Bordallo N, Kelley GR, Kyung-Ha N, Takeda A, Nagao T, Takahashi Y, Lizcano A, Carr AS, Graus F, Dalmau J. A novel treatment-responsive encephalitis with frequent opsoclonus and teratoma. Ann Neurol. 2014 Mar;75(3):435-41.
  • Kearney S, Carr AS, McConville J, McCarron MO on behalf of the Northern Ireland Neurology Network. Rhabdomyolysis secondary to co-prescription of statin and fusidic acid. Rhabdomyolysis after co-prescription of statin and fusidic acid. BMJ. 2012 Oct 9;345:e6562.
  • Dabner M, McCluggage WG, Bundell C, Carr A, Leung Y, Sharma R, Stewart CJ. Ovarian teratoma associated with anti-N-methyl D-aspartate receptor encephalitis: a report of 5 cases documenting prominent intratumoral lymphoid infiltrates. Int J Gynecol Pathol. 2012 Sep;31(5):429-37.
  • Palace J, Lashley D, Bailey S, Jayawant S, Carr AS, McConville J, Robb S, Beeson D. Clinical features in a series of fast channel congenital myasthenia syndrome. Neuromuscul Disord. 2012 Feb;22(2):112-7. doi: 10.1016/j.nmd.2011.08.002. Epub 2011 Sep 21.
  • Carr AS, Cardwell C, O’Reilly D, McCarron PO, McConville J. A systematic review of population based epidemiological studies of myasthenia gravis. BMC Neurol. 2010 Jun 18;10:46.
  • McColgan P, Carr AS, McCarron MO. Use and reliability of a neurohospitalist in a general hospital. Postgrad Med J. 2011 Mar;87(1025):166-9.
  • Carr AS, McConville J. A study of myasthenia gravis in Northern Ireland. Myasthenia Gravis Association News. December 2009.
  • Fitzpatrick AS, Gray OM, McConville J, McDonnell GV. Opsoclonus Myoclonus syndrome associated with benign ovarian teratoma. Neurology 2008; 70:1292-1293
  • Fitzpatrick AS, Loughrey CM, Johnston P, Spence W, Flynn P, McKee S, Jones FGC, Morrow JI. Haematopoietic stem cell transplant for adult cerebral adrenoleukodystrophy. Europ Journ Neurol. 2008; 15, e21-22.
  • Fitzpatrick AS, McCarron MO. Use and usefulness of a District General Hospital Neurologist. Postgrad Med J 2008; 84,988:109-110
  • Fitzpatrick AS. “Tours de France” A commentary on the similarities and differences between undergraduate medicine in Ireland and France. Trinity Student Medical Journal, 2003; 3; 68-69